18:I[34901,["/_next/static/chunks/1q_xs299ft_73.js","/_next/static/chunks/1hsg494-jz4os.js","/_next/static/chunks/1a25lc5cxtp8a.js","/_next/static/chunks/08v7mhpebw2l_.js"],"JobTable"] 19:T2065,

About this opportunity:

At Freenome, we are seeking a Senior Research Associate to help grow our Genomics Assay Development team. At Freenome, you will help develop the assay technologies used to analyze patient samples and contribute to our mission of early cancer detection. The ideal candidate will work to develop assay technologies for our multiomic platform manually and on robotic platforms. You will develop, characterize, verify, and validate clinical-grade assays to measure complex, blood-based analytes (e.g., whole-genome sequencing of cfDNA). You will work cross-functionally with Research & Development teams, automation and process engineering, computational science, and clinical operations to develop and transfer NGS-based assays in a regulated, high-throughput environment. You are passionate about developing life saving diagnostics using NGS technologies, and you will have a significant impact on the continued growth of an organization dedicated to changing the entire landscape of cancer.

The role reports to the Manager of Genomics Late Stage Development. This role will be an onsite role based in our Brisbane, California headquarters.

What you’ll do:

Apply knowledge of molecular biology, nucleic-acid biochemistry, and next-generation sequencing to develop assays for DNA, including genome-wide and targeted approaches
Participate in experimental design and independently plan and execute mission-critical experiments to optimize and characterize assay performance
Create and manipulate high impact assay inputs, including use of biological samples and formulation of contrived samples and reagents as required
Gather high-quality data, take detailed notes, and openly communicate on lessons learned while performing experiments
Perform data analysis, create summary presentations, and present results cross-functionally
Perform technical troubleshooting, identify and implement process improvements across the lab by thinking critically about the execution of all experiments
Build productive working relationships and collaborate with engineers and clinical laboratory members to transition development protocols into clinical production, including automation, validation experiments, and SOP development
Contribute to writing study protocols and reports. Diligently apply current Good Laboratory and Documentation Practices (cGLP, cGDP)

Must haves:

Bachelor’s or Master’s degree in molecular biology, biochemistry, genetics, or a related field with at least 4 years of professional experience in the life sciences. Prior experience in clinical diagnostics and/or working in a start-up environment is preferred
Experience executing verification and validation studies for IVD assays in a regulated laboratory environment (GLP)
Hands-on experience in Next-gen sequencing (NGS) based assay development including extraction, library preparation, target capture, and sequencing
Familiarity with molecular biology, genomics, NGS, assay development, sample preparation, reagent handling, or related laboratory workflows (e.g. plasma separation processes, DNA/RNA extraction, purification, and quantification, NGS library preparation)
Experience designing, planning, and executing successful experiments, interpreting results, preparing data for review, and giving effective scientific presentations
High attention to detail and ability to record accurate and detailed observations, assess impact, and perform troubleshooting as required
Ability to manually pipette with high confidence, accuracy, and precision
Clear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplines
Strong organizational skills and the ability to contribute the design and implementation of new processes
Flexible and highly motivated to learn new skills and comfortable adapting to changing priorities

Nice to haves:

Experience in working with with methylated ctDNA/cfDNA as an analyte in liquid biopsy workflows
Experience with automated liquid handlers, laboratory information systems, sample tracking systems, and equipment scheduling/status tools
Familiarity with programing in a scientific programming language (e.g., Python or R)

Additional information:

Contractors may be hired through a third-party provider and will be considered contingent workers. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.

Freenome is proud to be an equal opportunity employer and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.

California applicants please review the CCPA Notice at Collection here:

California Consumer Privacy Act (CCPA)

#LI-ONSITE

1a:T1605,

About this opportunity:

At Freenome, we are seeking a Contract Clinical Research Associate to help grow the Freenome Clinical Development team. The ideal candidate is well-organized, an excellent communicator and experienced in diagnostics clinical trial management. This person is responsible for all things related to assigned aspects of clinical trial monitoring and site management. You are passionate about clinical research, attention to detail and Good Clinical Practice, and you will have a significant impact on the continued growth of an organization dedicated to changing the entire landscape of cancer.

The role reports to the Director of Clinical Operations, Dennis McHugh. This role will be a Remote role with occasional travel, as required, to our Brisbane, California headquarters.

What you’ll do:

Ensure compliance with standard protocol and regulatory and ICH GCP obligations in assigned aspects of clinical site monitoring, such as site initiation, routine monitoring, maintenance of study files, study close out, and retrieval of study materials.
Complete on-site and remote monitoring activities in compliance with the Clinical Monitoring Plan, including source document verification for accuracy and integrity, as required.
Write and submit reports of investigational site findings and update applicable tracking systems, as required; escalate observed deficiencies and issues as appropriate.

Must haves:

Minimum Bachelor’s degree in a life science-related field, a registered nurse (RN) certification, or equivalent.
3+ years’ experience in a clinical trials research environment required, with specific in vitro diagnostics study experience.
General knowledge of regulatory requirements & GCP.
Ability to multi-task, deal with shifting priorities, and proactively solve problems/manage risks.
Strong interpersonal, collaborative, and time management abilities.
Excellent organizational skills; accurate and detail-oriented.
High proficiency in Veeva Vault and Medrio.
Strong spoken and written communication skills.

Nice to haves:

CRA certification by recognized professional organization is a plus, but not mandatory.
Previous experience in the cancer early detection space.

Additional information:

Applicants have rights under Federal Employment Laws.

California applicants please review the CCPA Notice at Collection here:

California Consumer Privacy Act (CCPA)

#LI-REMOTE

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Role	Company	Location	Season	Posted
Senior Research Associate (Contractor)	Freenome	Brisbane, CA, United States	—	3 months ago
Clinical Research Associate (Contractor)	Freenome	RemoteRemote	—	6 months ago